Multimodality Raman and photoacoustic imaging of surface-enhanced-Raman-scattering-targeted tumor cells

J Biomed Opt. 2016 Feb;21(2):20503.

Shi W, Paproski RJ, Shao P, Forbrich A, Lewis JD, Zemp RJ.


A multimodality Raman and photoacoustic imaging system is presented. This system has ultralow background and can detect tumor cells labeled with modified surface-enhanced-Raman-scattering (SERS) nanoparticles in vivo. Photoacoustic imaging provides microvascular context and can potentially be used to guide magnetic trapping of circulating tumor cells for SERS detection in animal models.


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Application of Surface-Enhanced Raman Spectroscopy to Guide Therapy for Advanced Prostate Cancer Patients

March 11, 2022

Congratulations to authors and APCaRI members Sunil Rajput, PhDDesmond Pink, Scott Findlay, Emma WoolnerJohn Lewis, and Mark McDermott on their recent publication in ACS Sensors! The authors demonstrate a novel assay that detects and quantifies a specific protein biomarker in serum from advanced prostate cancer patients, leading to better-informed prostate cancer treatment.

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