Translational Research

Translational Research

Translational research transforms scientific discoveries arising from fundamental studies into clinical applications to improve outcomes for patients with prostate cancer. Members of this team work together to employ innovative new technologies for biomarker discovery, detection and quantification that have been developed independently in internationally-recognized efforts in Alberta and bring them to bear on a common goal – developing better tests for prostate cancer.

The combination of prognostic biomarkers from distinct aspects of prostate cancer progression resulted in a test that is more sensitive, more accurate and more cost effective than current tests for prostate cancer.

Our overall goal is to improve patient outcomes and quality of life by translating novel tests to the clinic that are more sensitive, more accurate and more cost-effective than current tests for prostate cancer. No one dies from prostate cancer that is localized to the prostate – the spread, or metastasis, of prostate cancer is what makes it so dangerous. The five year survival rate for localized prostate cancer in North America is close to 100%, yet this drops to 30% for metastatic disease. The metastasis of prostate cancer is driven primarily by changes in growth factors, extracellular proteases, and the cell migration machinery. Biomarkers that are involved in these processes are prognostic for metastatic prostate cancer and their integration into a single powerful test are the focus of this multi-disciplinary team.

Our team is integrating internationally-recognized efforts in the characterization of tumour cell migration, growth factor signaling and protease-activated receptors to develop novel multiplex tests to more accurately predict outcomes in prostate cancer.

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Member of the APCaRI training program, Dr. Anais Medina Martin, selected as a remarkable woman for the International Women’s Day at the Caucus Meeting in Edmonton

Last March 8th, 2017 the Legislative Assembly of Alberta held a special session in order to celebrate the International Women’s Day in our province. Some of Elected Members of the Assembly invited one or two women from their constituency with an outstanding story to be celebrated in that special meeting. Among of that exquisite selection, Dr. Anais Medina Martin had the honor to be chosen, together with Mrs. Yvette Labiuk, as a member of the Department of Oncology at the University of Alberta.  This support is again reaffirming the personal potential that we host at the APCaRI.

- Anais Medina Martin