Publications

Publications

Metastasis as a therapeutic target in prostate cancer: a conceptual framework

By:
Contributors: Andries Zijlstra Research Group, Katie Hebron, John D. Lewis Research Group, David Bond, PhD, Konstantin Stoletov, PhD, Srijan Raha
Am J Clin Exp Urol. 2014 Apr;2(1):45-56.

Abstract

Metastasis is the main cause of prostate cancer-associated deaths. While significant progerss has been made in the treatment of primary tumors, efficent therapies that target the metastatic spread of prostate cancer are far from clinical reality. To efficiently treat cancer we need be able to impede its spread. Unfortunately, the majority of current therapeutics approved to treat metastatic cancer were originally selected based on their ability to inhibit primary tumor growth. This inherent flaw precluded these therapies from efficiently targeting the development of secondary metastatic lesions, a process that is distinct from that of primary tumor progression. In this review we will summarize the conceptual, cellular and molecular targets that should be considered to design effective anti-metastatic therapies.

 

PubMed

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Party with your prostate – Annual Comedy Series

Join us for this inaugural men’s night out filled with killer cocktails, comedy and culinary – all in support of prostate cancer research through the Cross Cancer Institute.

May 3, 2016
MKT Fresh Food & Beer Market (8101 Gateway Blvd)
6:00pm
Comedian: Artie Lange

Sorry ladies – men’s night out only!

Tickets are $500 each and will be held at the door in the cardholder’s name.
Tickets will also be available at the door

- Bird Dogs for Prostate Cancer Research