Publications

Publications

Detection of circulating tumor cells using targeted surface-enhanced Raman scattering nanoparticles and magnetic enrichment

By:
Contributors: Robert Paproski, PhD, Ronald Moore Research Group
J Biomed Opt. 2014 May;19(5):056014. doi: 10.1117/1.JBO.19.5.056014.

Abstract

While more than 90% of cancer deaths are due to metastases, our ability to detect circulating tumor cells (CTCs) is limited by low numbers of these cells in the blood and factors confounding specificity of detection. We propose a magnetic enrichment and detection technique for detecting CTCs with high specificity. We targeted both magnetic and surface-enhanced Raman scattering (SERS) nanoparticles to cancer cells. Only cells that are dual-labeled with both kinds of nanoparticles demonstrate an increasing SERS signal over time due to magnetic trapping.

PubMed

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Falling Walls Venture – Berlin 2018

Congratulations to John Lewis and Nanostics for winning an entry into the highly competitive and prestigious Falling Walls Venture Conference in Berlin, November 8-9, 2018!

Five presenters pitched their healthcare-related ideas and innovations to a panel of tech and business-savvy judges and a large audience on Aug 29, 2018, at the University of Alberta in a high-stakes “TEDTalk” meets “Dragon’s Den” style. The competition was tough but John Lewis edged out the fellow contenders to win a chance to pitch a 5-minute talk on Nanostics’ high-accuracy prostate cancer diagnostic reflex test: ClarityDX Prostate.

John talked with Mark Connolly from the CBC Edmonton Morning show on September 4 about the Falling Walls competition and what he is preparing for this November.

Good luck to John Lewis at the Falling Walls Finale in Berlin!

John Lewis wins an entry to Falling Walls Berlin!

- Perrin Beatty