Publications

Publications

Age, obesity, medical comorbidities and surgical technique are predictive of symptomatic anastomotic strictures after contemporary radical prostatectomy.

By:
Contributors: Geoffrey Gotto, MD
J Urol. 2011 Jun;185(6):2148-52. doi: 10.1016/j.juro.2011.02.003. Epub 2011 Apr 15.

Abstract

PURPOSE:

Anastomotic strictures are relatively common after radical prostatectomy and are associated with significant morbidity, often requiring multiple surgical interventions. There is controversy in the literature regarding which factors predict the development of anastomotic strictures. In this study we determined predictors of symptomatic anastomotic strictures following contemporary radical prostatectomy.

MATERIALS AND METHODS:

Between 1999 and 2007, 4,592 consecutive patients underwent radical prostatectomy without prior radiotherapy at our institution. Data were collected from prospective surgical and institutional morbidity databases, and retrospectively from inpatient and outpatient medical and billing records. Cases were assigned a Charlson score to account for comorbidities. Complications were graded according to the modified Clavien classification.

RESULTS:

Open radical prostatectomy was performed in 3,458 men (75%) and laparoscopic radical prostatectomy was performed in 1,134 (25%). The laparoscopic radical prostatectomy group included 97 robotic-assisted cases. Median patient age was 59.5 years (IQR 54.7, 64.2). Symptomatic anastomotic strictures developed in 198 patients (4%) after a median postoperative followup of 3.5 months (IQR 2.1, 6.1). On multivariate analysis significant predictors included patient age, body mass index, Charlson score, renal insufficiency, individual surgeon, surgical approach and the presence of postoperative urine leak or hematoma.

CONCLUSIONS:

Patient factors as well as technical factors influence the development of symptomatic anastomotic strictures following contemporary radical prostatectomy. The impact of these factors is influenced by the individual surgeon and the approach used.

 

PubMed

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Congratulations to top alumni honour awardee Dr. Ron Moore

Congratulations to Dr. Ron Moore, ’80 BSc, ’86 MD, ’91 PhD, who will receive an Alumni Honour Award from University of Alberta President David H. Turpin during the Alumni Awards Ceremony on Monday, Sept. 24, 2018, at the Northern Alberta Jubilee Auditorium in Edmonton.
The Alumni Honour Award recognizes the significant achievements and contributions by University of Alberta alumni to their profession and their community. Dr. Moore has made significant contributions to advancing our knowledge and treatment of bladder, kidney and prostate cancer. He has studied and developed laser treatment as therapy for prostate and bladder cancer, and developed new drugs to improve prostate cancer radiotherapy outcomes. Dr. Ron Moore has also actively mentored and trained hundreds of students throughout his career as well as serving on the APCaRI leadership committee.

The community is invited to celebrate as Dr. Ron Moore receives this top alumni award!
Date: Monday, Sept. 24, 2018
Location: Northern Alberta Jubilee Auditorium (11455 87 Ave), Edmonton, Alberta
Time: 7 p.m. ceremony with dessert reception to follow
Cost: Free, register for tickets
Dress: Business attire

For more information, please contact the Office of Alumni Relations at 780-492-3224, toll free 1-800-661-2593 or alumni@ualberta.ca
Featured at @UAlbertaAlumni and in the New Trail magazine.

- Perrin Beatty