Publications

Publications

Sedentary Behavior and Prostate Cancer Risk in the NIH-AARP Diet and Health Study

By:
Contributors: Karen A. Kopciuk, PhD
Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):882-9. doi: 10.1158/1055-9965.EPI-13-0808. Epub 2014 Feb 13.

Abstract

Sedentary behavior (sitting time) has been proposed as an independent risk factor for some cancers; however, its role in the development of prostate cancer has not been determined. We examined the prospective associations of self-reported daily sitting time and daily television/video viewing time with the risk of developing or dying from prostate cancer among 170,481 men in the NIH-AARP Diet and Health Study. We estimated HRs and 95% confidence intervals (CI) using Cox proportional hazards regression. Between 1996 and 2006, there were 13,751 incident (including 1,365 advanced) prostate cancer cases identified; prostate cancer mortality (through 2008) was 669. No strong or significant association with prostate cancer risk was seen in fully adjusted models for either daily sitting or television/video time. There were some suggestions of effect modification by body mass index (BMI; interaction for television/video time and BMI, P = 0.02). For total prostate cancer risk, television/video time was associated with a slightly elevated, but nonsignificant, increase amongst obese men (HR = 1.28; 95% CI, 0.98-1.69); a null association was observed amongst overweight men (HR = 1.04; 0.89-1.22); and, for men with a normal BMI, television/video time was associated with a nonsignificant risk decrease (HR = 0.82; 95% CI, 0.66-1.01). Similar patterns were observed for total daily sitting and television/video time in advanced prostate cancer and prostate cancer mortality. Sedentary behavior seems to play a limited role in the development of prostate cancer; however, we cannot rule out potential effect modification by BMI or the impact of measurement error on results.

PubMed

Download PDF

Stay Informed

To stay up to date on all the latest news and publications, subscribe to our newsletter!

APCaRI members participate in the Enbridge Ride to Conquer Cancer

Well, we did it!  Several APCaRI members participated in a 2-day major cycling event called the Enbridge Ride to Conquer Cancer, benefiting the Alberta Cancer Foundation. We cycled 228 kms over 2 days along the majestic Rockies with thousands of other Riders, supported by an amazing team of volunteers. Riding along with 34 members of the Cross Cancer Institute Team, and 1741 riders in total, it was an epic experience! The weather could not have been better, it was sunny, warm and the scenery was amazing.
Most importantly, we raised $7.8M to support cutting edge cancer research in Alberta. We are very thankful for the support we received, which will help us to beat prostate cancer.

If you didn’t get a chance to support one of our riders, please consider contributing to the team’s efforts at our DONATE page.

teamfinish

- John Lewis

Our International Network of Partners

Meeting these ambitious goals will not be possible without the committed engagement of our many partners across Alberta, Canada and the World. Learn more about our Partners.