Assistant Professor, Department of Agricultural, Food and Nutritional Science, University of Alberta
Dr. Carla Prado is an Assistant Professor at the University of Alberta in Canada, and a Campus Alberta Innovates (CAIP) Chair in Nutrition, Food and Health. She is the Director of the Human Nutrition Research Unit, a state-of-the-art research and training facility that supports cutting-edge research on the physiology and causes of nutritional problems through assessment of body composition, whole body energy metabolism, diet, and physical activity.
Dr. Prado is an expert in assessing nutritional status through the precise measurement of body composition and energy metabolism. Her research has shown for the first time the prevalence and clinical implications of sarcopenic obesity (concurrent appearance of low muscle and high fat) in cancer, and has provided evidence of the independent effect of body composition on cancer recurrence, treatment and survival. The focus of her current research program is to develop targeted nutrition interventions for the prevention and treatment of sarcopenia and sarcopenic obesity in patients with cancer.
Dr. Prado received her Ph.D. from the University of Alberta, Canada, and has completed further training at the Cross Cancer Institute (Canada), the National Institutes of Health (USA) and Newcastle University (UK). She is an Associate Editor of Clinical Nutrition and the Journal of Cachexia, Sarcopenia and Muscle, and has been recently recognized as a Fellow of the Obesity Society (USA).
- Carneiro IP, Mazurak VC, Prado CM. Clinical implication of sarcopenic obesity in cancer. Accepted: Current Oncology Reports.
- Cespedes EM, Bradshaw PT, Kroenke CH, Chen WY, Prado CM, Weltzien EK, Castillo AL, Caan BJ. Post-diagnosis Weight Change and Survival Following a Diagnosis of Early Stage Breast Cancer. Accepted: Cancer Epidemiology, Biomarkers and Prevention.
- Crawford J, Prado CM*, Johnston MA, Gralla RJ, Taylor RP, Hancock ML, Dalton, JT. Study Design and Rationale for the Phase 3 Clinical Program of Enobosarm, a Selective Androgen Receptor Modulator, for the Prevention and Treatment of Muscle Wasting in Cancer Patients (POWER Trials). * Co-first Author. Current Oncology Reports: 2016 Jun;18(6):37.
- MeyerhardtJ, KroenkeCH, Prado CM, Kwan M, Castillo A, Weltzien E, Xiao J, Caan Association of Weight Change after Colorectal Cancer Diagnosis and Outcomes in the Kaiser Permanente Northern California Population. Accepted: Cancer Epidemiology, Biomarkers and Prevention.
- KroenkeCH, Neugebauer R, MeyerhardtJ, Prado CM, Weltzien E, Kwan M, Xiao J, Caan Analysis of Body Mass Index and Mortality in Patients with Colorectal ancer Using Causal Diagrams. JAMA Oncology. Published online May 19, 2016. doi:10.1001/jamaoncol.2016.0732.
- Purcell S, Elliott S, Baracos VE, Prado CM. Key Determinants of Energy Expenditure in Cancer and Implications for Clinical Practice. Ahead of print: 2016, 1-9. doi:10.1038/ejcn.2016.96
- Cushen SJ, Power DG, Murphy KP, McDermott R, Griffin BT, Lim M, Daly L, Maceneaney P, O’Sullivan K, Prado CM, Ryan AM. Impact of body composition parameters on clinical outcomes in patients with metastatic castrate-resistant prostate cancer treated with docetaxel. Clinical Nutrition ESPEN 2016, v.13: e-39-45.
- Purcell S, Elliott SA, Kroenke CH, Sawyer MB, Prado CM. Impact of Body Weight and Body Composition on Ovarian Cancer Prognosis. Current Oncology Reports, 18(2): 1-11.
- Prado CM, Cushen S, Orsso C, Ryan A. Sarcopenia and Cachexia in the Era of Obesity: Clinical and Nutritional Impact. Proceeding of the Nutrition Society. 2016 May;75(2):188-98.
- Ryan AM, Power DG, Daly L, Cushen SJ, Bhuachalla EN, Prado CM. Cancer-associated malnutrition, cachexia and sarcopenia: The skeleton in the hospital closed 40 years later. Proceeding of the Nutrition Society. 2016 May;75(2):199-211.
- Prado CM, Gonzalez MC, Heymsfield SB. Body composition and obesity paradox. Current Opinion in Clinical Nutrition and Metabolic Care. 18(6): 535-51.
- Heyland D, Stapleton R, Mourtzakis M, Hough T, Morris P, Deutz NE, Colantuoni E, Day A, Prado CM, Needham DM. Combining nutrition and exercise to optimize survival and recovery from critical illness: conceptual and methodological issues. Clin Nutrition. Ahead of print: 2015 Jul 16. doi: 10.1016/j.clnu.2015.07.003.
- Siervo M, Prado C*, Hooper L, Munro A, Collerton J, Davies K, Kingston A, Mathers JC, Kirkwood TB, Jagger C. Serum osmolarity and haematocrit do not modify the association between the impedance index (Ht(2)/Z) and total body water in the very old: The Newcastle 85+ Study. Archives of Gerontology and Geriatrics. 2015;60(1):227-32. *co-first author
- Prado CM, Heymsfield S. Lean Tissue Imaging: A New Era for Nutritional Assessment and Intervention. Journal of Parenteral and Enteral Nutrition. 2014; 38(8):940-53.
- de van der Schueren M, Elia M, Gramlich L, Johnson MP, Lim SL, Philipson T, Prado CM. Clinical and economic outcomes of nutrition interventions across the continuum of care. Annals of the New York Academy of Sciences. 2014; 1321:20-40.
- Prado CM, Siervo M, Mire E, Heymsfield SB, Stephan BC, Broyles S, Smith SR, Wells J, Katzmarzyk PT. A Population-Based Approach to Define Body Composition Phenotypes. American Journal of Clinical Nutrition. 2014; 99(6):1369-1377.
- Prado CM, Baracos VE, Xiao J, Birdsell L, Stuyckens K, Choi Park, Youn, Parekh T, Sawyer MB. The association between body composition and toxicities from the combination of doxil and trabectedin in patients with advanced relapsed ovarian cancer. Applied Physiology, Nutrition, and Metabolism. 2014; 39(6):693-8.
- Prado CM. Sawyer MB, Ghosh S, Lieffers JR, Esfandiari N, Antoun S, Baracos V. The central tenet of cancer cachexia therapy: do patients with advanced cancer have exploitable anabolic potential? American Journal of Clinical Nutrition, 2013; 98(4):1012-9.
- Prado CM. Body composition in chemotherapy: the promising role of CT scans. Current Opinion in Clinical Nutrition and Metabolic Care, 2013; 16(5):525-33.