Adam Kinnaird, MD PhD FRCSC

Frank and Carla Sojonky Chair in Prostate Cancer Research and Surgeon


Surgery / Oncology

Chair of APCaRI
Frank and Carla Sojonky Chair in Prostate Cancer Research
Division of Urology, Department of Surgery
University of Alberta

Adam Kinnaird is a Surgeon, Scientist, Chair of APCaRI, and the Frank and Carla Sojonky Chair in Prostate Cancer Research, in the Division of Urology, Department of Surgery at the University of Alberta. The Sojonky Chair was endowed to the Alberta Cancer Foundation by the late Frank Sojonky and a team of volunteers known as the Bird Dogs and supports research that will help us better understand, diagnose, and treat prostate cancer.  Adam completed a fellowship in Imaging, Targeted Biopsy, and Focal Therapy for Prostate Cancer at UCLA. His lab studies translational prostate cancer research with a focus on new drugs, technologies, and devices. He was a varsity athlete and graduate of the University of Alberta, having won two national championships while he was a member of the Golden Bears men’s ice hockey team. Adam completed his MD and Urology residency at the U of A, during which he was enrolled in the Clinician Investigator Program. He completed his PhD as a Vanier Scholar and was awarded the Governor General’s Gold Medal in research. Adam has published in high-impact journals such as Nature Reviews Cancer, Cell, and European Urology and has been awarded funding from local, regional, and national grant competitions since starting as an Assistant Professor in November 2020

Relevant Publications

 Kinnaird A, Brisbane W, Kwan L, Priester A, Chuang R, Barsa D, Delfin M, Sisk A, Margolis D, Felker E, Hu J, Marks LS. A prostate cancer risk calculator (PCRC-MRI): Use of Clinical+MRI data to predict biopsy outcome. (2020) Under review at Journal of Urology

Kinnaird A, Sharma V, Chuang R, Priester A, Tran E, Barsa D, Delfin M, Kwan L, Sisk A, Felker E, Marks LS. Risk of prostate cancer after a negative MRI-guided biopsy (2020) In Revision at Journal of Urology

Chuang R*, Kinnaird A*, Kwan L, Sisk A, Barsa D, Felker E, Delfin M, Marks LS. Hemi-gland cryoablation of clinically significant prostate cancer: intermediate-term follow-up via MRI-guided biopsy. (2020) IN PRESS at Journal of Urology *Co-first authors 

Kinnaird A, Boukouris A, Saleme B, Dromparis P, Zervopoulos SD, Gurtu V, Sutendra G, Michelakis D. VHL attenuates p53-dependent gene expression. (2020) In revision at Journal of Molecular Medicine

 Norris J, Kinnaird A, Margolis D, Padhani A, Walz J, Kasivisvanathan V. Developments in MRI-targeted prostate biopsy. (2020) Current Opinion in Urology 30(1): 1-8

 Kinnaird A, Zemp L, Rasmussen A, Senthilselvan, A, Chetner M, Rourke K, Schuler T. Balancing patient care with resident well-being: Analysis of changes to Urology resident inpatient workload in a universal healthcare system over a decade. (2019) Urology Practice IN PRESS

Priester A, Kinnaird A, Zhou S, Jayadevan R, Rappaport M, Delfin M, Felker E, Marks L. Focal Therapy of Prostate Cancer: Use of Tracked Biopsy Sites to Determine Treatment Margins (2019) Submitted to Journal of Urology 

Ballon J, Kinnaird A, Jayadevan R, Zhou S, Barsa D, Kwan L, Marks L. MRI-guided Biopsy to Evaluate Prostate Cancer Severity in African-American Men. (2019) Urology Practice IN PRESS

 Guorgui J, Kinnaird A, Jayadevan R, Priester A, Arnold C, Marks L. An electronic form for reporting results from targeted prostate biopsy: Urology Integrated Diagnostic Report (Uro-IDR). (2020) Urology IN PRESS 

Bain A, Kinnaird A, McLarty R, Senthilselvan A, Todd G, Chetner M. Oncological outcomes of salvage cryotherapy after primary radiation therapy versus primary cryotherapy: 10-year experience at a large Canadian referral center. (2019) CUAJ IN PRESS

 Kinnaird A and Michelakis ED. The time has come to pull renal cancer’s sweet tooth. (2019) Transl Cancer Res 8(Suppl 2):S156-S161

Saleme B, Gurtu V, Kinnaird A, Boukouris A, Wagg C, Lopaschuk G, Sutendra G. Differential regulation of p53 transcriptional activity and apoptosis by Pyruvate Kinase M2 can be therapeutically targeted in chemotherapy-induced cardiotoxicity. (2019) Science Translational Medicine 11(478)

Kinnaird A, Dromparis P, Evans H. Recurrence and upstaging rates of T1 high grade urothelial carcinoma of the bladder on repeat resection in a Canadian, resource limited, healthcare system. (2018) CUAJ 12(8):267-269

Chapman D, Cotter K, Johnsen N, Patel S, Kinnaird A, Erickson B, Voelzke B, Buckley J, Rourke K. Non-transecting techniques reduce sexual dysfunction after anastomotic bulbar urethroplasty: Results of a multi-institutional comparative analysis. (2018) Journal of Urology 201(2):364-370

 Michelakis ED, Gurtu V, Webster L, Barnes G, Watson G, Howard L, Cupitt J, Paterson I, Thompson R, Chow K, O’Regan D, Zhao L, Wharton J, Kiely D, Kinnaird A, Boukouris AE, White C, Nagendran J, Freed D, Gibbs S, Wilkins MR. Inhibition of pyruvate dehydrogenase kinase improves pulmonary arterial hypertension in genetically susceptible patients. (2017) Science Translational Medicine 9(413)

 Chapman D, Kinnaird A, Rourke KF. Independent Predictors of Stricture Recurrence Following Urethroplasty for Isolated Bulbar Urethral Strictures. (2017) Journal of Urology 198(5):1107-1112

 Kinnaird A, Zhao S, Wellen KE, Michelakis ED. Metabolic Control of Epigenetics in Cancer. (2016) Nature Reviews Cancer 16(11):694-707

 Kinnaird A, Dromparis P, Saleme B, Gurtu V, Watson K, Paulin R, Zervopoulos S, Stenson T, Sutendra G, Pink DB, Carmine-Simmen K, Moore R, Lewis JD and Michelakis ED. Metabolic Modulation of Clear-cell Renal Cell Carcinoma with Dichloroacetate, an Inhibitor of Pyruvate Dehydrogenase Kinase. (2016) European Urology 69(4):734-44

Rourke KF, Kinnaird A, Zorn J. Observations and outcomes of urethroplasty for bulbomembranous stenosis after radiation therapy for prostate cancer. (2016) World Journal of Urology 34(3):377-82

Forbes E, Cheung D, Kinnaird A, and St. Martin B. Zero Ischemia Robotic-Assisted Partial Nephrectomy in Alberta: Initial Results of a Novel Approach. (2015) Canadian Urological Association Journal 9(3-4):128-32

 Kinnaird A, and Michelakis ED. Metabolic Modulation of Cancer: A new frontier with great translational potential. (2015) Journal of Molecular Medicine 93(2):127-42.

Sutendra G, Kinnaird A, Dromparis P, Paulin R, Stenson TH, Haromy A, Hashimoto K, Zhang N, Flaim E and Michelakis ED. A functional nuclear pyruvate dehydrogenase complex is important for a mitochondria-independent generation of acetyl-CoA and histone acetylation. (2014) Cell 158(1):84-97

Levine M, Kinnaird A, and Rourke K. Revision urethroplasty successes is comparable to primary urethroplasty: A comparative analysis. (2014) Urology 84(4):928-32

Kinnaird A, Levine M, Ambati D, Zorn J, and Rourke K. Stricture length and etiology as preoperative independent predictors of recurrence after urethroplasty: A multivariate analysis of 604 urethroplasties. (2014) Canadian Urological Association Journal 8(5-6), e296-300

Sutendra G, Dromparis P, Kinnaird A, Stenson TH, Haromy A, Parker JM, McMurtry MS, Michelakis ED. Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer (2013). Oncogene; 32(13):1638-50

 Hoy NY, Kinnaird A, Rourke KF. Expanded use of a dorsal onlay augmented anastamotic urethroplasty with buccal mucosa for long segment bulbar urethral strictures: analysis of outcomes and complications. (2013) Urology 81(6):1357-61

Manolescu AR, Witkowska K, Kinnaird A, Cessford T, Cheeseman C. (2007) Facilitated hexose transporters: new perspectives on form and function. Physiology 22:234-40


Surgery / Oncology

Chair of APCaRI
Frank and Carla Sojonky Chair in Prostate Cancer Research
Division of Urology, Department of Surgery
University of Alberta