Karen A. Kopciuk, PhD

Contact

Departments of Oncology, & Mathematics and Statistics
University of Calgary

Population Health Research, Cancer Control Alberta
E-mail: Karen.Kopciuk@albertahealthservices.ca
Tel: 403-220-2833 (Temporary)

Research Scientist at Alberta Health Services, Department of Population Health Research, Adjunct Associate Professor at the University of Calgary

Dr. Kopciuk obtained her PhD in Statistics from the University of Waterloo in Waterloo, Ontario in 2001 followed by a post-doctoral fellowship at the Samuel Lunenfeld Research Institute in Toronto, Ontario in Statistical Genetics. Dr. Kopciuk has expertise in experimental study designs including retrospective and prospective cohort designs. In addition, she has expertise in estimating sample sizes for discovery and validation phases of biomarker research.


Relevant Publications

Lynch BM, Friedenreich CM, Kopciuk KA, Hollenbeck AR, Moore SC, Matthews CE. Sedentary Behavior and Prostate Cancer Risk in the NIH-AARP Diet and Health Study. Cancer Epidemiol Biomarkers Prev. 2014 May;23(5):882-9.

Thirukkumaran CM, Shi ZQ, Luider J, Kopciuk K, Bahlis N, Neri P, Pho M, Stewart D, Mansoor A, Morris DG. Reovirus as a successful ex vivo purging modality for multiple myeloma. Bone Marrow Transplant. 2014 Jan;49(1):80-6.

Choi YH, Briollais L, Green J, Parfrey P, Kopciuk K. Estimating successive cancer risks in Lynch Syndrome families using a progressive three-state model. Stat Med. 2014 Feb 20;33(4):618-38.

Sapkota Y, Mackey JR, Lai R, Franco-Villalobos C, Lupichuk S, Robson PJ, Kopciuk K, Cass CE, Yasui Y, Damaraju S. Assessing SNP-SNP interactions among DNA repair, modification and metabolism related pathway genes in breast cancer susceptibility. PLoS One. 2013 Jun 3;8(6):e64896.

Thirukkumaran CM, Shi ZQ, Luider J, Kopciuk K, Gao H, Bahlis N, Neri P, Pho M, Stewart D, Mansoor A, Morris DG. Reovirus modulates autophagy during oncolysis of multiple myeloma. Autophagy. 2013 Mar;9(3):413-4.

McGregor SE, Courneya KS, Kopciuk KA, Tosevski C, Friedenreich CM. Case-control study of lifetime alcohol intake and prostate cancer risk. Cancer Causes Control. 2013 Mar;24(3):451-61.

Aparicio-Ting FE, Friedenreich CM, Kopciuk KA, Plotnikoff RC, Bryant HE. Prevalence of meeting physical activity guidelines for cancer prevention in Alberta. Chronic Dis Inj Can. 2012 Sep;32(4):216-26.

Thirukkumaran CM, Shi ZQ, Luider J, Kopciuk K, Gao H, Bahlis N, Neri P, Pho M, Stewart D, Mansoor A, Morris DG. Reovirus as a viable therapeutic option for the treatment of multiple myeloma. Clin Cancer Res. 2012 Sep 15;18(18):4962-72.

Farshidfar F, Weljie AM, Kopciuk K, Buie WD, Maclean A, Dixon E, Sutherland FR, Molckovsky A, Vogel HJ, Bathe OF. Serum metabolomic profile as a means to distinguish stage of colorectal cancer. Genome Med. 2012 May 14;4(5):42.

Otsuka S, Klimowicz AC, Kopciuk K, Petrillo SK, Konno M, Hao D, Muzik H, Stolte E, Boland W, Morris D, Magliocco AM, Bebb DG. CXCR4 overexpression is associated with poor outcome in females diagnosed with stage IV non-small cell lung cancer. J Thorac Oncol. 2011 Jul;6(7):1169-78.

Boffetta P, Colditz GA, Potter JD, Kolonel L, Robson PJ, Malekzadeh R, Seminara D, Goode EL, Yoo KY, Demers P, Gallagher R, Prentice R, Yasui Y, O’Doherty K, Petersen GM, Ulrich CM, Csizmadi I, Amankwah EK, Brockton NT, Kopciuk K, McGregor SE, Kelemen LE. Cohorts and consortia conference: a summary report (Banff, Canada, June 17-19, 2009). Cancer Causes Control. 2011 Mar;22(3):463-8.

Bathe OF, Shaykhutdinov R, Kopciuk K, Weljie AM, McKay A, Sutherland FR, Dixon E, Dunse N, Sotiropoulos D, Vogel HJ. Feasibility of identifying pancreatic cancer based on serum metabolomics. Cancer Epidemiol Biomarkers Prev. 2011 Jan;20(1):140-7.

Kopciuk KA, Choi YH, Parkhomenko E, Parfrey P, McLaughlin J, Green J, Briollais L. Penetrance of HNPCC-related cancers in a retrolective cohort of 12 large Newfoundland families carrying a MSH2 founder mutation: an evaluation using modified segregation models. Hered Cancer Clin Pract. 2009 Oct 28;7(1):16.

Friedenreich CM, Gregory J, Kopciuk KA, Mackey JR, Courneya KS. Prospective cohort study of lifetime physical activity and breast cancer survival. Int J Cancer. 2009 Apr 15;124(8):1954-62.

Choi YH, Kopciuk KA, Briollais L. Estimating disease risk associated with mutated genes in family-based designs. Hum Hered. 2008;66(4):238-51.

Nottage MK, Kopciuk KA, Tzontcheva A, Andrulis IL, Bull SB, Blackstein ME. Analysis of incidence and prognostic factors for ipsilateral breast tumour recurrence and its impact on disease-specific survival of women with node-negative breast cancer: a prospective cohort study. Breast Cancer Res. 2006;8(4):R44.

Kopciuk KA, Briollais L, Demenais F, Bull SB. Using an age-at-onset phenotype with interval censoring to compare methods of segregation and linkage analysis in a candidate region for elevated systolic blood pressure. BMC Genet. 2003 Dec 31;4 Suppl 1:S84.

Gladman DD, Farewell VT, Kopciuk KA, Cook RJ. HLA markers and progression in psoriatic arthritis. J Rheumatol. 1998 Apr;25(4):730-3.

Contact

Departments of Oncology, & Mathematics and Statistics
University of Calgary

Population Health Research, Cancer Control Alberta
E-mail: Karen.Kopciuk@albertahealthservices.ca
Tel: 403-220-2833 (Temporary)